![]() The disease varies according to its origination point in the biliary tract. Tim Greten : Bile duct cancer, also known as cholangiocarcinoma, is a disease of the tiny tubes that carry bile from the liver, where bile is made, and the gallbladder, where it’s stored, to the small intestine, where it helps digest fats in food and detoxify potentially harmful substances. He discussed work with patients, who’s at risk, the difficulties of diagnosis, and other aspects of bile duct cancer with Everyday Health.Įveryday Health: What is bile duct cancer? Still, he has seen remarkable “super responders” persist long after their diagnosis - enough for him to cultivate a “glass half-full” approach to these cancers. That drops to 9 percent (up to 25 percent if diagnosed early) for intrahepatic bile duct cancer, which occurs within the liver.ĭevoting a medical career to this complicated disease has been an admittedly tough challenge, says Tim Greten, MD, a medical oncologist trained in gastroenterology and the senior investigator and co-director of the liver cancer program at the National Cancer Institute in Bethesda, Maryland. The American Society of Clinical Oncology (ASCO) estimates the five-year survival rate for people with what’s known as extrahepatic bile duct cancer (which occurs outside the liver) at around 10 percent (17 if diagnosed early). Historically, these cancers have been tough to treat. ![]() Bile duct cancer affects the pathways within and leading from the liver, a football-sized organ tucked between the diaphragm and the stomach that performs a variety of important functions. When the transit of this life-sustaining fluid is disrupted, as happens in the rare bile duct cancers called cholangiocarcinomas, things can get nasty. It’s no coincidence that “full of bile” is a phrase used to describe ill-tempered people.
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